San Francisco's Premier Dental TITI4D Studio

Your Most
Radiant
Smile Yet.

World-class cosmetic and implant dentistry in the heart of San Francisco's historic Mission District — where artistry meets precision.

15+
Years Experience
4.9★
Patient Rating
5K+
Happy Smiles
Dental Angel on a Mission clinic reception Modern dental treatment room
15+
Years of Excellence

Where Beautiful Smiles Are Crafted

Nestled in San Francisco's vibrant Mission District, Dental Angel on a Mission has been transforming smiles and changing lives for over a decade. Under the expert guidance of Managing Partner Issa George Karkar, our practice combines cutting-edge dental technology with a warm, compassionate approach to care.

We believe every patient deserves a smile they're proud of — and an experience that feels effortless. From routine cleanings to full smile makeovers, we treat each case as a work of art.

Award-Winning Care
Recognized among SF's top dental practices for patient satisfaction and clinical outcomes.
Latest Technology
Digital X-rays, 3D imaging, CAD/CAM restorations, and laser dentistry.
Patient-First Philosophy
Every treatment plan is tailored to your unique goals, anatomy, and budget.
Insurance Friendly
We work with most major dental insurance plans and offer flexible payment options.

Comprehensive Dental Services

From your first visit to your final reveal, we offer every dental service you need — all under one beautifully designed roof.

02

Cosmetic Dentistry

Transform your smile with our full range of aesthetic treatments — whitening, bonding, contouring, and complete smile makeovers.

Explore Options
03

Invisalign

Straighten your teeth discreetly with clear, removable aligners. No wires, no brackets — just a beautifully aligned smile on your timeline.

Start Your Journey
05

Emergency Dental

Dental emergencies don't wait — neither do we. Same-day emergency appointments available for pain relief, broken teeth, and urgent care.

Call Now
06

General Dentistry

Preventive care is the foundation of great oral health. Exams, cleanings, fillings, root canals — we handle it all with precision and care.

Schedule Checkup
Dr. Issa George Karkar, Managing Partner and Lead Dentist

Led by Passion,
Driven by Precision

"Every patient deserves not just a healthy smile, but a smile that tells their story beautifully. That's what we work toward every single day."

Issa George Karkar brings over 15 years of specialized experience in cosmetic and implant dentistry. Trained at leading institutions across the United States, he combines clinical mastery with an artist's eye — ensuring every smile is as unique as the person wearing it.

DDS, University of California Invisalign Certified Provider Implant Specialist ADA Member CDA Member SFDS Member

What Our Patients Say

4.9 avg · 284 reviews

Dr. Karkar completely transformed my smile. I had veneers done on 8 teeth and the results were beyond anything I imagined. My confidence has skyrocketed. The whole team made me feel so comfortable throughout the process.

Maria Santos
Porcelain Veneers Patient · ⭐⭐⭐⭐⭐

Had a dental emergency on a Saturday afternoon — cracked a tooth badly. They got me in within the hour. The care was incredible, completely pain-free. I'm now a patient for life. This is what great dentistry looks like.

James T.
Emergency Dental Patient · ⭐⭐⭐⭐⭐

I was terrified of implants — the idea just scared me. Dr. Karkar walked me through every single step and made the whole process so easy. 6 months later and my implant looks and feels exactly like a real tooth. Worth every penny.

Rebecca Chen
Dental Implant Patient · ⭐⭐⭐⭐⭐

Answers You Need

We believe in transparency. Here are the questions we hear most — answered clearly, without the dental jargon.

Yes, we work with most major dental insurance providers including Delta Dental, Aetna, Cigna, MetLife, and United Healthcare. Please call our office at +1 (415) 872-0915 to confirm your specific plan's coverage before your first appointment.
Implant costs depend on complexity, bone density, and whether you need additional procedures like bone grafting. We offer free consultations with a detailed, transparent treatment plan and pricing. Financing options are available. Contact us to get started.
Most Invisalign treatments take between 6–18 months depending on the complexity of misalignment. Mild cases can sometimes be completed in as little as 3–6 months. During your free consultation, Dr. Karkar will provide a personalized treatment timeline.
Absolutely. We offer same-day emergency appointments for toothaches, broken teeth, lost fillings, and other dental urgencies. Call +1 (415) 872-0915 immediately — we will do our very best to see you the same day, even for new patients.
Traditional porcelain veneers are considered a permanent procedure because a small amount of enamel is removed to place them. However, they typically last 10–20 years before needing replacement. We also offer minimal-prep and no-prep veneers in select cases.
We're open Monday–Friday 9:00 AM – 6:00 PM and Saturday 9:00 AM – 5:00 PM. We are closed on Sundays. For emergency care outside of office hours, please call our main line and follow the prompts for after-hours emergency guidance.
Address
2172 Mission Street
San Francisco, CA 94110
Mission District
Hours
Mon–Fri: 9am–6pm
Saturday: 9am–5pm
Sunday: Closed
Rating
4.9 / 5.0 Stars
284+ Verified Reviews
Google & Yelp

We're in the Heart of the Mission

Address
2172 Mission Street
San Francisco, CA 94110
United States
Get Directions →
Office Hours
Monday – Friday9:00 AM – 6:00 PM
Saturday9:00 AM – 5:00 PM
SundayClosed
Getting Here
BART: 16th St Mission Station (0.3 mi)
MUNI Lines: 14, 14R, 49 on Mission St. Street parking and paid lots nearby.

Your Dream Smile
Starts Today

Book a complimentary consultation and discover exactly what's possible for your smile — no pressure, no commitment.